D Janczewskiosiagnieciapublikacje 2021

Influence of lipid bilayer composition on the activity of antimicrobial quaternary ammonium ionenes, the interplay of intrinsic lipid curvature and polymer hydrophobicity, the role of cardiolipin

By 30 sierpnia, 2021 No Comments

W czasopiśmie Colloids and Surfaces B (vol 207,  112016) ukazała się nasza nowa publikacja: „Influence of lipid bilayer composition on the activity of antimicrobial quaternary ammonium ionenes, the interplay of intrinsic lipid curvature and polymer hydrophobicity, the role of cardiolipin.”

by: Rafał J. Kopiasz, Alicja Rukasz, Karolina Chreptowicz, Rafał Podgórski, Aleksandra Kuźmińska, Jolanta Mierzejewska, Waldemar Tomaszewski, Tomasz Ciach, Dominik Jańczewski

Highlights:

• Series of ionenes with substantial bioactivity against model microorganisms.

• An unusual drop of activity following increase of polymer hydrophobicity.

• Vesicles containing cardiolipin are sensitive toward more hydrophilic ionenes.

• For certain vesicles and concentrations hydrophobic ionenes can reduce release of a dye.